Born in Hiroshima, Japan, Itoso's passion for animation was evident from a young age. While in university, he honed his skills on commercial animation projects and showcased his talent as a manga artist. In 1998, he was accepted into Studio Ghibli's prestigious Tobukodai Village Camp, where he apprenticed under the legendary director Hayao Miyazaki, a pivotal experience that shaped his artistic vision.

Seeking broader horizons, Itoso ventured overseas, where his career took on an international dimension. He directed and produced a diverse range of projects, including the original anime "Coruboccoro," which received support from the Tokyo Metropolitan Government. His work has been showcased at prestigious events such as the Cannes Film Festival, cementing his reputation as a rising star in the global animation scene.

Itoso is equally passionate about education. At the age of 32, he became a professor at Osaka Seikei University, where he revolutionized the curriculum by introducing industry-academia collaboration and providing students with hands-on learning opportunities. His dedication to fostering the next generation of animators is a testament to his commitment to the industry's future.

Itoso's work has garnered numerous awards, including the Grand Prix and International Award at the METI-sponsored CMT Awards, the Tokyo Anime Award, and the Hokkaido Governor's Award at the Yubari International Fantastic Film Festival. Recognized as a New Artist by the Agency for Cultural Affairs in 2006, he continues to receive widespread acclaim for his groundbreaking contributions.